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Argireline: How it works in Anti-Aging Creams

by Julie Samtsonn

Wrinkles in the facial skin have various causes. They are part of the natural aging process, as skin cells lose fat content, elastin and collagen, over exposure to the sun over a period of time, and repetitive facial gestures, such as squinting or pursing the lips in the case of smoking. In addition, the skin cells lose their ability to retain moisture, as the fat contents become depleted, causing once plump cells, to take on the look of shriveled, dead skin cells and the underlying facial muscles to lay in a position they have been trained over time. This is where the smile lines, frown lines, eyebrow and forehead lines and crow’s feet lines start forming.

The aim of anti aging creams is to prevent lines and crinkle from appearing. The aim of anti wrinkle creams is to retrain skin to seal in moisture and the skin muscles to relax all of the positions they have formed over many years. There are strategies to ‘rebuild skin structure’ or ‘remodel skin cells’ that many people know about. To do this, it usually means the use of peptides. Peptides heal wounds very much like the way a burn victim will have their skin remodeled to encourage the skin to grow again.

Facial and skin muscle regrowth or retrain uses peptides like a muscle relaxer. Peptides will work on a deeper level than topical cream treatments. Argireline is the trade name for the ingredient ‘Acetyl Hexapeptides-3′ which is a synthetic anti aging chemical that is made from natural proteins that make a chain of amino acids. This chain of amino acids can then be used to stimulate things like muscle relaxation as well as reflex reaction, both of which can be a cause of wrinkles.

Argireline has been found successful to reduce the muscle reactions over a period of time, with slight improvement over a 4 week period, and twice the results in a 27 week usage. As with any anti aging cream or anti wrinkle cream treatment, once it is stopped, it is usual that the wrinkles will reappear to an extent and the natural muscle reactions will cause the newer skin cells to become retrained to appear to wrinkle with the fold of the underlying skin muscles.

Argireline, by the nature of it’s treatment of the underlying muscles versus treatment of the surface skin cells, make it much like a topical form of what Botox, by injection to the muscles does. The relaxation of the facial muscle contractions is a temporary solution, even with Botox. Manufacturers of Argireline use less than a 10% ingredient composure, as a higher concentration could have adverse effects, by relaxing the facial muscles too much and resulting in sagging. While Argireline has not been on the market long enough to measure long-term effects, it appears safe and effective as an ingredient in topical anti aging creams and anti wrinkle creams, and is available in many formulations on the market.

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